Associations of upper‐ and lower‐limb muscle strength, mass, and quality with health‐related quality of life in community‐dwelling older adults.

Aim: This study aimed to investigate the associations between upper‐ and lower‐limb muscle strength, mass, and quality and health‐related quality of life (HRQoL) among community‐dwelling older adults. Methods: A cross‐sectional study was conducted with 428 Brazilian community‐dwelling older adults aged 60 to 80 years. Upper‐ and lower‐limb muscle strength were evaluated through the handgrip strength (HGS) test and the 30‐s chair stand test, respectively. Muscle mass was assessed by dual‐energy X‐ray absorptiometry (DXA) and bioelectrical impedance analysis (BIA). Muscle quality was evaluated using the muscle quality index (MQI). HRQoL was assessed using the World Health Organization Quality of Life Brief Version questionnaire. Results: Lower‐limb, but not upper‐limb, muscle strength and quality were independently associated with HRQoL, particularly within the domains of physical capacity, environment, and overall HRQoL for both males and females (P < 0.05). DXA‐ and BIA‐derived analyses provided similar results in relation to muscle mass and muscle quality. Conclusions: Lower‐limb, but not upper‐limb, muscle strength and quality were independently associated with HRQoL among community‐dwelling older adults. Moreover, the results obtained from both BIA and DXA were similar, highlighting that BIA can serve as a viable surrogate method for estimating body composition in resource‐limited clinical settings. Geriatr Gerontol Int 2024; 24: 683–692. [ABSTRACT FROM AUTHOR]