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Nanoparticles as Drug Delivery Systems for the Targeted Treatment of Atherosclerosis.

Authors :
Pang, Alexander Shao-Rong
Dinesh, Tarini
Pang, Natalie Yan-Lin
Dinesh, Vishalli
Pang, Kimberley Yun-Lin
Yong, Cai Ling
Lee, Shawn Jia Jun
Yip, George W.
Bay, Boon Huat
Srinivasan, Dinesh Kumar
Source :
Molecules. Jun2024, Vol. 29 Issue 12, p2873. 26p.
Publication Year :
2024

Abstract

Atherosclerosis continues to be a leading cause of morbidity and mortality globally. The precise evaluation of the extent of an atherosclerotic plaque is essential for forecasting its likelihood of causing health concerns and tracking treatment outcomes. When compared to conventional methods used, nanoparticles offer clear benefits and excellent development opportunities for the detection and characterisation of susceptible atherosclerotic plaques. In this review, we analyse the recent advancements of nanoparticles as theranostics in the management of atherosclerosis, with an emphasis on applications in drug delivery. Furthermore, the main issues that must be resolved in order to advance clinical utility and future developments of NP research are discussed. It is anticipated that medical NPs will develop into complex and advanced next-generation nanobotics that can carry out a variety of functions in the bloodstream. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
14203049
Volume :
29
Issue :
12
Database :
Academic Search Index
Journal :
Molecules
Publication Type :
Academic Journal
Accession number :
178185156
Full Text :
https://doi.org/10.3390/molecules29122873