Application of metal-organic frameworks in infectious wound healing.

Highlights: The structural composition and morphological characteristics of the MOFs are described. The synthesis methods of MOF materials are described, and the effects of postmodification methods on MOF materials are described; The antimicrobial mechanism and classification of MOF materials and the antimicrobial characteristics of Ag-, Cu-, and Zn-based MOF materials are described. This paper highlights the challenges in the development of MOF materials and provides an outlook on the future of MOF materials. Metal-organic frameworks (MOFs) are metal-organic skeleton compounds composed of self-assembled metal ions or clusters and organic ligands. MOF materials often have porous structures, high specific surface areas, uniform and adjustable pores, high surface activity and easy modification and have a wide range of prospects for application. MOFs have been widely used. In recent years, with the continuous expansion of MOF materials, they have also achieved remarkable results in the field of antimicrobial agents. In this review, the structural composition and synthetic modification of MOF materials are introduced in detail, and the antimicrobial mechanisms and applications of these materials in the healing of infected wounds are described. Moreover, the opportunities and challenges encountered in the development of MOF materials are presented, and we expect that additional MOF materials with high biosafety and efficient antimicrobial capacity will be developed in the future. [ABSTRACT FROM AUTHOR]