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Focal epilepsy followed by rapidly progressive frontotemporal dementia: a rare manifestation of <italic>VCP</italic> mutation.

Authors :
Carlucci, Valentina
Salvalaggio, Alessandro
Riguzzi, Pietro
Fasolato, Davide
Bussè, Cinzia
Cecchin, Diego
Cagnin, Annachiara
Source :
Amyotrophic Lateral Sclerosis & Frontotemporal Degeneration. Jul2024, p1-3. 3p. 1 Illustration.
Publication Year :
2024

Abstract

This document is a letter to the editor discussing a rare manifestation of a VCP mutation. The case report describes a 58-year-old woman who experienced focal epilepsy followed by rapidly progressive frontotemporal dementia. The woman had a family history of dementia and behavioral changes. Neurological examination revealed frontal lobe syndrome, and brain imaging showed frontal lobe atrophy and hypometabolism. Genetic testing confirmed a mutation in the VCP gene. The authors emphasize the importance of genetic testing and imaging in diagnosing neurological disorders and highlight the heterogeneity of VCP-related disorders. [Extracted from the article]

Details

Language :
English
ISSN :
21678421
Database :
Academic Search Index
Journal :
Amyotrophic Lateral Sclerosis & Frontotemporal Degeneration
Publication Type :
Academic Journal
Accession number :
178311228
Full Text :
https://doi.org/10.1080/21678421.2024.2370809