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Pregnancy‐associated atypical hemolytic uremic syndrome. Case report.
- Source :
-
Journal of Obstetrics & Gynaecology Research . Jul2024, Vol. 50 Issue 7, p1268-1272. 5p. - Publication Year :
- 2024
-
Abstract
- Pregnancy‐associated atypical hemolytic uremic syndrome (P‐aHUS) is a rare disease. There are only few reports in the literature, and most are in the puerperium period. It is a thrombotic microangiopathy (TMA) characterized for microangiopathic hemolytic anemia, thrombocytopenia, and renal dysfunction. We report the case of a pregnant patient at 26.3 gestation weeks, who developed clinical features of TMA, neurological alterations, and septic shock; then after fetus and placental delivery, no clinical improvement was observed; a diagnostic protocol was performed due to suspicion of P‐aHUS, showing improvement after the plasma exchange sessions and eculizumab. We present here a brief review of the case since it is an entity that needs to be suspected during pregnancy when TMA features and requires an immediate diagnosis to provide timely treatment. [ABSTRACT FROM AUTHOR]
- Subjects :
- *HEMOLYTIC-uremic syndrome diagnosis
*DIAGNOSIS of blood diseases
*BLOOD disease treatment
*HEMOLYTIC-uremic syndrome treatment
*PLATELET count
*CREATININE
*RARE diseases
*ASPARTATE aminotransferase
*PLASMAPHERESIS
*HEMODIALYSIS
*LACTATE dehydrogenase
*MEAN platelet volume
*THROMBOCYTOPENIA
*NEUROLOGICAL disorders
*SEPTIC shock
*MONOCLONAL antibodies
*GESTATIONAL age
*ALANINE aminotransferase
*URINALYSIS
*PREGNANCY complications
*PLASMA exchange (Therapeutics)
*DEXAMETHASONE
*PREGNANCY
Subjects
Details
- Language :
- English
- ISSN :
- 13418076
- Volume :
- 50
- Issue :
- 7
- Database :
- Academic Search Index
- Journal :
- Journal of Obstetrics & Gynaecology Research
- Publication Type :
- Academic Journal
- Accession number :
- 178317731
- Full Text :
- https://doi.org/10.1111/jog.15958