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Pregnancy‐associated atypical hemolytic uremic syndrome. Case report.

Authors :
Barrera‐Hoffmann, Christopher
Mariaca‐Ortíz, Yadira
Ruiz‐Villa, Josué Giovani
Cuevas‐Cruz, Lesllie Eugenia
López‐Mendoza, María del Rosario
Briones‐Garduño, Jesús Carlos
Source :
Journal of Obstetrics & Gynaecology Research. Jul2024, Vol. 50 Issue 7, p1268-1272. 5p.
Publication Year :
2024

Abstract

Pregnancy‐associated atypical hemolytic uremic syndrome (P‐aHUS) is a rare disease. There are only few reports in the literature, and most are in the puerperium period. It is a thrombotic microangiopathy (TMA) characterized for microangiopathic hemolytic anemia, thrombocytopenia, and renal dysfunction. We report the case of a pregnant patient at 26.3 gestation weeks, who developed clinical features of TMA, neurological alterations, and septic shock; then after fetus and placental delivery, no clinical improvement was observed; a diagnostic protocol was performed due to suspicion of P‐aHUS, showing improvement after the plasma exchange sessions and eculizumab. We present here a brief review of the case since it is an entity that needs to be suspected during pregnancy when TMA features and requires an immediate diagnosis to provide timely treatment. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
13418076
Volume :
50
Issue :
7
Database :
Academic Search Index
Journal :
Journal of Obstetrics & Gynaecology Research
Publication Type :
Academic Journal
Accession number :
178317731
Full Text :
https://doi.org/10.1111/jog.15958