Mitochondrial Damage Induced by Excess Growth Hormone in Glomerular Podocytes: Implications in Diabetic Nephropathy.

This article, titled "Mitochondrial Damage Induced by Excess Growth Hormone in Glomerular Podocytes: Implications in Diabetic Nephropathy," explores the role of growth hormone (GH) in podocyte injury and its connection to diabetic nephropathy. The study investigates the effects of GH on podocyte morphology and function using in vivo and in vitro models. The findings suggest that GH leads to enhanced intracellular calcium influx, altered mitochondrial dynamics, and decreased ATP production in podocytes. The authors propose that targeting mitochondrial damage could be a potential therapeutic approach to prevent diabetic nephropathy. [Extracted from the article]