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Artificial Intelligence Predicts Sensitivity of EGFR Novel Mutations to Tyrosine Kinase Inhibitors.

Authors :
Kumar, Raunak
Sanjeev, Airy
Devi, Naorem Leimarembi
Shinde, Isha
Khan, Asif
Saldanha, Elveera
Poojary, Disha
Ishaqwala, Fiza
Banavali, S. D.
Dutt, Amit
Noronha, Vanita
Prabhash, Kumar
Choughule, Anuradha
Chandrani, Pratik
Source :
Indian Journal of Medical & Paediatric Oncology. 2024 Supplement 1, Vol. 45, pS1-S16. 16p.
Publication Year :
2024

Abstract

This article, titled "Artificial Intelligence Predicts Sensitivity of EGFR Novel Mutations to Tyrosine Kinase Inhibitors," explores the use of molecular dynamics simulations and machine learning techniques to predict the response of tyrosine kinase inhibitors (TKIs) in cancer patients. The study focuses on EGFR mutations and their interactions with TKIs. The researchers developed an artificial intelligence model with high accuracy for predicting EGFR TKI sensitivity. The findings suggest that this model could be a valuable tool for determining drug sensitivity in patients. [Extracted from the article]

Details

Language :
English
ISSN :
09715851
Volume :
45
Database :
Academic Search Index
Journal :
Indian Journal of Medical & Paediatric Oncology
Publication Type :
Academic Journal
Accession number :
178340866
Full Text :
https://doi.org/10.1055/s-0044-1788220