Letter to the editor for the article "Comparison of ciprofloxacin versus fosfomycin versus fosfomycin plus trimethoprim/sulfamethoxazole for preventing infections after transrectal prostate biopsy".

This letter to the editor responds to a study comparing different antibiotic prophylaxis regimens for transrectal prostate biopsy. The study found that a combination of two antibiotics, FMT and TMP/SMX, provided protection against post-intervention infections comparable to that of Ciprofloxacin. However, the letter raises concerns about the potential adverse effects of antibiotics, particularly renal toxicity, and suggests incorporating renal toxicity assessment into future studies. The letter also mentions that the risk of infection can be reduced by using transperineal prostate puncture biopsy instead of transrectal biopsy. The authors express gratitude for the study and declare no competing interests. [Extracted from the article]