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New half sandwich complexes of ruthenium(ii) and iridium(iii). Study of their toxicity against Hela.
- Source :
-
Pure & Applied Chemistry . Jul2024, p1. 11p. 5 Illustrations. - Publication Year :
- 2024
-
Abstract
- In this work, we describe the synthesis and characterisation of the starting materials [Cp*IrCl2]2 and four new ruthenium(II) and iridium(III) complexes half sandwich, contain the fragments [(p-cymene)Ru]2+ and [Cp*Ir]2+; (Cp* = CpMe4Et) of stoichiometry: [Cp*IrCl2(2-aminopyridine)] (I), [Cp*IrCl2(4-aminopyridine)] (II), [Cp*IrCl2(adenine)] (III) and [(<italic>p</italic>-cymene)RuCl2(adenine)] (IV). The new compounds have been characterised by C, H, and N elemental analysis; infrared and 1H NMR spectroscopy with 1H–1H COSY, ESI/TOF mass spectrometry and thermogravimetry. A study of the cytotoxicity of these compounds against the Hela cell line was carried out, with results indicating a low activity. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 00334545
- Database :
- Academic Search Index
- Journal :
- Pure & Applied Chemistry
- Publication Type :
- Academic Journal
- Accession number :
- 178371378
- Full Text :
- https://doi.org/10.1515/pac-2024-0224