Immediate‐type allergy to d‐limonene and anethole in toothpaste.

This article discusses a case report of an 8-year-old girl who experienced shortness of breath and an itchy nose when brushing her teeth with different brands of toothpaste. Skin prick tests and open patch tests revealed that she had an immediate-type allergy to an aroma mixture called Optamint®, which contained the substances d-limonene and anethole. These substances are commonly used as fragrance and flavoring agents in various products. The findings suggest that fragrance ingredients in toothpaste can cause immediate-type allergies, and it is important to identify the specific allergens in order to address the issue. [Extracted from the article]