Antiviral Drug Discovery.

This document is an editorial from the International Journal of Molecular Sciences titled "Antiviral Drug Discovery." It highlights the urgent need for antiviral agents, especially in light of the COVID-19 pandemic. The editorial discusses the success of HIV-1 and influenza antivirals in managing these diseases, but also emphasizes the challenges of emerging viruses and drug resistance. The document covers various topics related to antiviral drug discovery, including in silico studies for SARS-CoV-2, new targets for HIV-1, IAV antiviral drugs, and the mechanism of baicalin inhibiting IBV. It also addresses the evaluation of interactions between antivirals and the immune system. The editorial concludes by thanking the authors, reviewers, and journal staff for their contributions. [Extracted from the article]