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40 years of researching the Del phenotype results in a change of transfusion practice.
- Source :
-
Transfusion . Jul2024, Vol. 64 Issue 7, p1187-1190. 4p. - Publication Year :
- 2024
-
Abstract
- KEY IDEAS: Anti‐D cannot agglutinate red cells of any Del phenotype in routine serology.Many individuals with East Asian ancestry who type D‐negative in serology harbor a Del phenotype.Almost all such individuals carry one distinct DEL variant, dubbed Asian‐type DEL, known as RHD*01EL.01, RHD*DEL1, RHD:c.1227G>A, formerly known as RHD(K409K).Clinical evidence strongly suggests that Asian‐type DEL individuals can safely be transfused with RhD‐positive blood and do not need anti‐D prophylaxis in pregnancy. [ABSTRACT FROM AUTHOR]
- Subjects :
- *PHENOTYPIC plasticity
*EAST Asians
*ERYTHROCYTES
*PHENOTYPES
Subjects
Details
- Language :
- English
- ISSN :
- 00411132
- Volume :
- 64
- Issue :
- 7
- Database :
- Academic Search Index
- Journal :
- Transfusion
- Publication Type :
- Academic Journal
- Accession number :
- 178468988
- Full Text :
- https://doi.org/10.1111/trf.17913