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Ultrasound-guided lesser occipital nerve combined with great auricular nerve block for vestibular schwannoma craniotomy via a suboccipital retrosigmoid approach: a prospective, double-blind randomized controlled trial.
- Source :
-
BMC Anesthesiology . 7/20/2024, Vol. 24 Issue 1, p1-11. 11p. - Publication Year :
- 2024
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Abstract
- Purpose: This aim of this study was to investigate the analgesic efficacy and safety of lesser occipital nerve combined with great auricular nerve block (LOGAB) for craniotomy via a suboccipital retrosigmoid approach. Methods: Patients underwent vestibular schwannoma resection via a suboccipital retrosigmoid approach were randomly assigned to receive ultrasound-guided unilateral LOGAB with 5 ml of 0.5% ropivacaine (LOGAB group) or normal saline (NSB group). Numeric rating scale (NRS) scores at rest and motion were recorded within 48 h after surgery. Mean arterial pressure (MAP), heart rate (HR), opioid consumption and other variables were measured secondly. Results: Among 59 patients who were randomized, 30 patients received ropivacaine, and 29 patients received saline. NRS scores at rest (1.8 ± 0.5 vs. 3.2 ± 0.8, P = 0.002) and at motion (2.2 ± 0.7 vs. 3.2 ± 0.6, P = 0.013) of LOGAB group were lower than those of NSB group within 48 h after surgery. NRS scores of motion were comparable except for 6th and 12th hour (P < 0.05) in the LOGAB group. In LOGAB group, MAP decreased significantly during incision of skin and dura (P < 0.05) and intraoperative opoid consumption was remarkably reduced (P < 0.01). Postoperative remedial analgesia was earlier in the NSB group (P < 0.001). No patients reported any adverse events. Conclusion: Among patients undergoing craniotomy for vestibular schwannoma via a suboccipital retrosigmoid approach, LOGAB may be a promising treatment for perioperative analgesia and has the potential to maintain intraoperative hemodynamic stability. Clinical trial registration number: Chictr.org.cn ChiCTR2000038798. [ABSTRACT FROM AUTHOR]
- Subjects :
- *OCCIPITAL bone
*EXTERNAL ear
*LOCAL anesthetics
*PATIENT safety
*PHYSIOLOGIC salines
*BLIND experiment
*STATISTICAL sampling
*ROPIVACAINE
*POSTOPERATIVE pain
*CRANIOTOMY
*ULTRASONIC imaging
*RANDOMIZED controlled trials
*DESCRIPTIVE statistics
*HEMODYNAMICS
*ACOUSTIC neuroma
*ANALGESICS
*LONGITUDINAL method
*DRUG efficacy
*NERVE block
*INNERVATION
Subjects
Details
- Language :
- English
- ISSN :
- 14712253
- Volume :
- 24
- Issue :
- 1
- Database :
- Academic Search Index
- Journal :
- BMC Anesthesiology
- Publication Type :
- Academic Journal
- Accession number :
- 178526745
- Full Text :
- https://doi.org/10.1186/s12871-024-02642-2