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Advances in the use of organoids in endometrial diseases.
- Source :
-
International Journal of Gynecology & Obstetrics . Aug2024, Vol. 166 Issue 2, p502-511. 10p. - Publication Year :
- 2024
-
Abstract
- The endometrium undergoes cyclical changes in response to hormones and there is a certain degree of heterogeneity among individuals. In vivo identification of the physiologic changes of the endometrium and the pathologic process of related diseases is challenging. There have been recent advances in the use of organoids that mimic the characteristics of the corresponding organs and the morphologic, functional, and personalized characteristics involved in different stages of diseases. In this paper, we discuss the process of creating endometrial organoids, cell sources, types of extracellular matrices, and their application in the study of physiologic endometrial states and various diseases. Synopsis: The paper explores endometrial organoids, their use in studying physiologic states and diseases, and recent advancements in this field. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 00207292
- Volume :
- 166
- Issue :
- 2
- Database :
- Academic Search Index
- Journal :
- International Journal of Gynecology & Obstetrics
- Publication Type :
- Academic Journal
- Accession number :
- 178531716
- Full Text :
- https://doi.org/10.1002/ijgo.15422