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Complete hematologic response in a patient with multiple pretreated angioimmunoblastic T‐cell lymphoma after belinostat therapy followed by allogeneic stem cell transplantation: A case report.

Authors :
De Wilde, Sigrid
Graux, Carlos
Source :
Clinical Case Reports. Jul2024, Vol. 12 Issue 7, p1-8. 8p.
Publication Year :
2024

Abstract

Key Clinical Message: Belinostat therapy followed by hematopoietic stem cell transplantation is a promising salvage strategy for heavily pretreated patients with peripheral T‐cell lymphoma. Effective treatments for peripheral T‐cell lymphoma in the relapsed and refractory (r/r) setting are limited. However, with the development and approval of innovative therapies, effective therapeutic options are becoming available for this patient population. This case report describes the treatment course of a patient with multiple r/r nodal follicular T‐helper cell lymphoma of angioimmunoblastic type. Treatment with the histone deacetylase inhibitor belinostat as bridging, enabled allogeneic stem cell transplantation and resulted in a durable complete hematologic response for at least 21 months post‐transplantation. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
20500904
Volume :
12
Issue :
7
Database :
Academic Search Index
Journal :
Clinical Case Reports
Publication Type :
Academic Journal
Accession number :
178558745
Full Text :
https://doi.org/10.1002/ccr3.9159