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Deciphering the enigma of Lassa virus transmission dynamics and strategies for effective epidemic control through awareness campaigns and rodenticides.

Authors :
Hamam, Haneen
Ramzan, Yasir
Niazai, Shafiullah
Gepreel, Khaled A.
Awan, Aziz Ullah
Ozair, Muhammad
Hussain, Takasar
Source :
Scientific Reports. 8/5/2024, Vol. 14 Issue 1, p1-22. 22p.
Publication Year :
2024

Abstract

This study aims to formulate a mathematical framework to examine how the Lassa virus spreads in humans of opposite genders. The stability of the model is analyzed at an equilibrium point in the absence of the Lassa fever. The model's effectiveness is evaluated using real-life data, and all the parameters needed to determine the basic reproduction number are estimated. Sensitivity analysis is performed to pinpoint the crucial parameters significantly influencing the spread of the infection. The interaction between threshold parameters and the basic reproduction number is simulated. Control theory is employed to devise and evaluate strategies, such as awareness campaigns, advocating condom usage, and deploying rodenticides to reduce the possibility of virus transmission efficiently. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
20452322
Volume :
14
Issue :
1
Database :
Academic Search Index
Journal :
Scientific Reports
Publication Type :
Academic Journal
Accession number :
178837302
Full Text :
https://doi.org/10.1038/s41598-024-68600-7