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D-Limonene Inhibits Pichia kluyveri Y-11519 in Sichuan Pickles by Disrupting Metabolism.

Authors :
Zeng, Chaoyi
Sun, Yue
Lin, Haoran
Li, Ziyu
Zhang, Qing
Cai, Ting
Xiang, Wenliang
Tang, Jie
Yasurin, Patchanee
Source :
Molecules. Aug2024, Vol. 29 Issue 15, p3561. 17p.
Publication Year :
2024

Abstract

The Pichia kluyveri, a proliferation commonly found in Sichuan pickles (SCPs), can accelerate the growth and reproduction of spoilage bacteria, causing off-odor development and decay. Although D-limonene, a common natural preservative, effectively restricts P. kluyveri, its inhibitory mechanism remains unclear. This study aimed to elucidate this molecular mechanism by investigating the impact on basic P. kluyveri metabolism. The findings revealed that D-limonene inhibited P. kluyveri growth and disrupted the transcription of the genes responsible for encoding the enzymes involved in cell wall and membrane synthesis, oxidative phosphorylation, glycolysis, and the tricarboxylic acid (TCA) cycle pathway. The results indicated that these events disrupted crucial metabolism such as cell wall and membrane integrity, adenosine triphosphate (ATP) synthesis, and reactive oxygen species (ROS) balance. These insights provided a comprehensive understanding of the inhibitory effect of D-limonene on the growth and reproduction of P. kluyveri while highlighting its potential application in the SCP industry. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
14203049
Volume :
29
Issue :
15
Database :
Academic Search Index
Journal :
Molecules
Publication Type :
Academic Journal
Accession number :
178948765
Full Text :
https://doi.org/10.3390/molecules29153561