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VCL::ROS1 : A Novel ROS1 Oncogenic Fusion Detected on Next Generation Sequencing.

Authors :
Mehta, Anurag
Diwan, Himanshi
Nathany, Shrinidhi
Batra, Ullas
Gupta, Manoj
Panigrahi, Manoj Kumar
Kumar, Dushyant
Mattoo, Sakshi
Singh, Aayushi
Source :
Clinical Pathology. 8/12/2024, p1-4. 4p.
Publication Year :
2024

Abstract

Advanced Non-Small Cell Lung Carcinoma (NSCLC) patients with ROS1 gene rearrangement have shown significant therapeutic responses to tyrosine kinase inhibitors approved by the US Food and Drug Administration, with approximately 40 fusion partners documented in the existing literature. Our report highlights a novel fusion partner of ROS1 that has demonstrated a conclusive response to the current standard of treatment. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
2632010X
Database :
Academic Search Index
Journal :
Clinical Pathology
Publication Type :
Academic Journal
Accession number :
178994123
Full Text :
https://doi.org/10.1177/2632010X241269373