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Multiplexed silencing of 2S albumin genes in peanut.

Authors :
Conner, Joann A.
Guimaraes, Larissa Arrais
Zhang, Zhifen
Marasigan, Kathleen
Chu, Ye
Korani, Walid
Ozias‐Akins, Peggy
Source :
Plant Biotechnology Journal. Sep2024, Vol. 22 Issue 9, p2438-2440. 3p.
Publication Year :
2024

Abstract

This article discusses the use of CRISPR-Cas9 gene editing technology to silence the 2S albumin genes in peanuts, which are known to be potent allergens. The researchers successfully edited the genes using a multiplex gene editing strategy and confirmed the elimination of the allergenic proteins through protein analysis. However, further testing is needed to determine if the edited peanuts have reduced allergenicity. The study was supported by Ukko, Inc. and the data supporting the findings are available in the supplementary material of the article. [Extracted from the article]

Details

Language :
English
ISSN :
14677644
Volume :
22
Issue :
9
Database :
Academic Search Index
Journal :
Plant Biotechnology Journal
Publication Type :
Academic Journal
Accession number :
179090761
Full Text :
https://doi.org/10.1111/pbi.14357