Clinical application of JAK inhibitors in SAPHO syndrome.

This article, published in the International Journal of Rheumatic Diseases, provides a comprehensive analysis of the clinical application of JAK inhibitors in SAPHO syndrome. SAPHO syndrome is a rare autoimmune inflammatory disease characterized by skin lesions, bone and joint lesions, and peripheral tissue damage. The study includes a retrospective analysis of 10 SAPHO syndrome patients, detailing their clinical data and treatment outcomes. The most common symptoms observed in these patients were sternoclavicular pain and swelling, joint pain in limbs, palmoplantar pustulosis, and severe acne. The article also includes clinical scores and radiographic images to support the findings. The study suggests that JAK inhibitors may be an effective treatment option for SAPHO syndrome, but emphasizes the importance of personalized treatment for optimal outcomes. [Extracted from the article]