Lichen planus after COVID‐19 infection and vaccination.

Background: Lichen planus is one of the common adverse reactions after COVID‐19 infection and vaccination. Despite it being reported in several case reports, the literature including a large sample of the studied population is lacking. The current study was performed to assess the risk of LP after COVID‐19 infection as well as COVID‐19 vaccination. Methods: The current study was designed as a retrospective cross‐sectional hospital‐based study of registered patients at the University of Florida (UF) health centers. The diagnoses of LP, COVID‐19 infection, and COVID‐19 vaccines were detected. The logistic regression model was used to assess the risk of developing LP after COVID‐19 infection and vaccination. Results: A total hospital patient of 684,110 attended UF Health centers were included in this study. 181 patients reported LP after COVID‐19 vaccination and 24 patients developed LP after COVID‐19 infection. The risk of developing LP after COVID‐19 vaccination was 1.573 while the risk of developing LP after COVID‐19 infection was 1.143. Conclusion: The odds of getting LP after COVID‐19 vaccination are significantly developed. The current study showed that COVID‐19 infection and vaccination are associated with LP. So, healthcare practitioners should be aware of this reaction for rapid recognition and treatment. [ABSTRACT FROM AUTHOR]