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Priority list of pharmaceutical active compounds in aquatic environments of Mexico considering their occurrence, environmental and human health risks.

Authors :
Hernández-Tenorio, Rafael
Villanueva-Rodríguez, Minerva
Guzmán-Mar, Jorge Luis
Hinojosa-Reyes, Laura
Hernández-Ramírez, Aracely
Vigil-Castillo, Héctor H.
Source :
Environmental Toxicology & Pharmacology. Sep2024, Vol. 110, pN.PAG-N.PAG. 1p.
Publication Year :
2024

Abstract

Pharmaceutical active compounds (PhACs) are detected pollutants in aquatic environments worldwide at concentrations ranging from ng L−1 to µg L−1. Currently, PhAC monitoring is poorly realized in Mexico. This study proposes a priority list of PhACs in Mexican aquatic environments, considering their occurrence and environmental and human health risks. Ecological risks were assessed as Risk Quotients (RQ) values using the PhAC concentrations detected in surface water, obtaining high risks (RQ > 1) against aquatic organisms, especially of naproxen, ibuprofen, diclofenac, acetaminophen, 17β-estradiol , carbamazepine, ketoprofen , caffeine. In contrast, potential human health risks (RQ H) were assessed on the Mexican population using the concentrations quantified in groundwater, demonstrating potential risks (RQ H > 0.2) on the population, particularly of DCF and CBZ. Thus, a priority list of PhACs can be used as a reference for environmental monitoring in Mexican water supplies as well as PhACs monitoring in countries of the Caribbean region and Central America. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
13826689
Volume :
110
Database :
Academic Search Index
Journal :
Environmental Toxicology & Pharmacology
Publication Type :
Academic Journal
Accession number :
179420601
Full Text :
https://doi.org/10.1016/j.etap.2024.104502