亚麻木酚素在干预疾病中涉及的信号通路及作用机制.

In recent years, the growing public awareness of personal health has sparked a surge in interest in the beneficial effects of polyphenols on the human organism. Extensive research by domestic and international scholars has established that polyphenols, due to their unique chemical properties, exhibit remarkable anti-inflammatory and antioxidant properties, leading to improvements in various diseases, including cancer, diabetes, and colitis. Notably, China stands as one of the world’s largest producers and consumers of flax, a crop rich in lignans, a subclass of polyphenols. These flax lignans possess significant effects on the body, demonstrating immense potential for therapeutic applications. This paper delves into the origins, metabolic processes, and health benefits of flax lignans in China. It offers a comprehensive review of the mechanisms underlying flax lignans role in disease intervention, focusing on their interactions with relevant signalling pathways. Our findings suggest that flaxseed lignans can promote organismic health by either directly modulating gene expression or indirectly regulating signalling pathways. Furthermore, flaxseed lignans can exhibit diverse effects depending on specific physiological conditions. [ABSTRACT FROM AUTHOR]