Granuloma annulare and the risk of autoimmune conditions: a multicentre retrospective cohort analysis.

A study published in the British Journal of Dermatology examined the association between granuloma annulare (GA), an inflammatory skin condition, and various autoimmune conditions. The study analyzed data from the TriNetX Research Network, which included 88 healthcare organizations, and identified 53,505 patients with GA who were matched with a control group. The results showed that patients with GA had a significantly increased risk of systemic lupus erythematosus, rheumatoid arthritis, type 1 diabetes mellitus, and autoimmune thyroiditis. The study also found potential associations with systemic sclerosis and uveitis, but further research is needed to confirm these findings. The study provides valuable insight into the risk of autoimmune disorders in people with GA. [Extracted from the article]