تباين مؤشرات الأداء النفسي العصبي لدى بعض مرضى التصلب المتناثر في ضوء معامل الادخار المعرفي ومدة المرض.

The aim of the current research is to explore the impact of cognitive reserve (CR) and disease duration on the cognitive performance in multiple sclerosis patients. The research sample included (40) MS outpatients were recruited, their average age was (32.13), with a standard deviation of 8.41 years, same as females (62.5%). CR was assessed by the vocabulary test and level of education. Cognitive assessment was performed using the Wechsler Adult Intelligence Scale - fourth edition (WAIS-IV) as a neuropsychological instrument tool to evaluate Verbal Comprehension Index, perceptual reasoning, working memory and processing speed. The results showed low performance in intelligence among (87.50%) of the sample, and the prevalence of cognitive dysfunction associated with multiple sclerosis was characterized by poor performance on the indicators of working memory and processing speed, as they occupied the highest level of prevalence rates (81.25%), followed by the Perceptual Reasoning Index (75%), then the Verbal Comprehension Index (68.75%). Cognitive impairment (CI) was found in all performance indicators in approximately (43.75%) of patients, and in three indicators in more than a third of patients (37.50%). Furthermore, 12.5% of patients had low performance on at least one or two indicators. Both the total disease duration and the CR factor - specifically measured by level of education - contributed to explaining the score on the Neuropsychological Performance Indicators in MS patients. [ABSTRACT FROM AUTHOR]