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Effects of Alcohol and Its Relationship with Deranged Liver Function Tests and Withdrawal Symptoms.

Authors :
Thangarajan, Remitha Joseph
Sureshkumar, Kailash
Kailash, Shabeeba Z.
Manogaran, Aravindh
Source :
Journal of Chemical Health Risks. 2024, Vol. 14 Issue 3, p617-626. 10p.
Publication Year :
2024

Abstract

Alcohol consumption is an important risk factor for illness, disability, and mortality. Alcohol withdrawal symptoms have a significant health concern for individuals with alcohol dependence. This study aims to investigate the prevalence of withdrawal symptoms and liver function test abnormalities in this population and also to identify the factors associated with the severity of withdrawal symptoms. This cross-sectional study was conducted at a tertiary care facility involving 100 patients seeking treatment for alcohol dependence. Data collection included structured interviews and assessments using standardized scales and biochemical tests. Descriptive statistics, t-tests, and chi-square tests were employed to analyse the data. Individuals exhibiting mild/moderate alcohol withdrawal symptoms in this study displayed several distinctive features. They were more likely to have attained at least a high school education, their average alcohol consumption was notably lower, Importantly, their blood parameters, including RBC count, platelet count, total bilirubin levels, and liver enzyme levels (AST and ALT), generally exhibited fewer deviations from normal ranges. Family history of alcohol dependence and nicotine dependence was common among the participants. This research highlights the need for a holistic approach to address alcohol dependence, taking into consideration sociodemographic factors, clinical markers, and the diverse nature of this condition. The findings provide important insights for healthcare professionals to identify individuals at higher risk and guide treatment decisions. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
22516719
Volume :
14
Issue :
3
Database :
Academic Search Index
Journal :
Journal of Chemical Health Risks
Publication Type :
Academic Journal
Accession number :
179862157
Full Text :
https://doi.org/10.60829/jchr.2024.1917