MRI 多序列扫描在肝细胞癌诊断和微血管侵犯评估中的应用价值.

Objective: To explore the application value of magnetic resonance imaging (MRI) multi-sequence scan in the diagnosis of hepatocellular carcinoma (HCC) and evaluation of microvascular invasion (MVI). Methods: A retrospective collection was performed on the clinical data of 100 patients with suspected HCC in the hospital between October 2019 and October 2022. All completed MRI multi-sequence scan and pathological examination. Taking pathological examination as the golden standard, the consistency between MRI multi-sequence scan and pathological examination in the diagnosis of HCC and evaluation of MVI was analyzed by Kappa test. Results: Among the 100 patients, pathological examination showed that there were 51 cases (51.00%) with HCC and 49 cases (49.00%) with benign liver lesions. In the 51 HCC patients, there were 17 cases (33.33%) with MVI. Taking pathological examination as the golden standard, sensitivity, specificity and Kappa values of T2WI in the diagnosis of HCC and MVI were (82.35%, 79.59%, 0.620) and (64.71%, 85.29%, 0.507), respectively. The sensitivity, specificity and Kappa values of TIWI in the diagnosis of HCC and MVI were (76.47%, 81.63%, 0.580) and (58.82%, 88.24%, 0.492), respectively. The sensitivity, specificity and Kappa values of LAVA in the diagnosis of HCC and MVI were (84.31%, 83.67%, 0.580) and (64.71%, 91.18%, 0.585), respectively. The sensitivity, specificity and Kappa values of MRI multi-sequence scan in the diagnosis of HCC and MVI were (96.08%, 79.59%, 0.759) and (94.12%, 82.35%, 0.712), respectively. The sensitivity of MRI multi-sequence scan was higher than that of single sequence (P<0.05). The proportions of unsmooth tumor edge and peritumoral enhancement in patients with MVI positive were higher than those with MVI negative (P<0.05). Conclusion: MRI multi-sequence scan is conductive to clinical diagnosis of HCC and evaluation of MVI. Unsmooth tumor edge and peritumoral enhancement have predictive significance in HCC and MVI. [ABSTRACT FROM AUTHOR]