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IgA nephropathy: Correlation between pathologic findings and complement activation.

Authors :
Haas, Mark
Source :
Nephrology. Sep2024 Supplement 1, Vol. 29, p60-62. 3p.
Publication Year :
2024

Abstract

Summary at a glance: Complement plays a vital role in the pathogenesis of IgA nephropathy. Kidney biopsies with IgA nephropathy show glomerular immune complex deposits with evidence of complement activation by the alternative pathway and in a subset of cases the mannose binding lectin pathway. The recent development of specific drugs targeting these complement pathways represent a potentially important new approach to treating IgA nephropathy. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
13205358
Volume :
29
Database :
Academic Search Index
Journal :
Nephrology
Publication Type :
Academic Journal
Accession number :
179962858
Full Text :
https://doi.org/10.1111/nep.14342