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IgA nephropathy: Correlation between pathologic findings and complement activation.
- Source :
-
Nephrology . Sep2024 Supplement 1, Vol. 29, p60-62. 3p. - Publication Year :
- 2024
-
Abstract
- Summary at a glance: Complement plays a vital role in the pathogenesis of IgA nephropathy. Kidney biopsies with IgA nephropathy show glomerular immune complex deposits with evidence of complement activation by the alternative pathway and in a subset of cases the mannose binding lectin pathway. The recent development of specific drugs targeting these complement pathways represent a potentially important new approach to treating IgA nephropathy. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 13205358
- Volume :
- 29
- Database :
- Academic Search Index
- Journal :
- Nephrology
- Publication Type :
- Academic Journal
- Accession number :
- 179962858
- Full Text :
- https://doi.org/10.1111/nep.14342