宏基因组二代测序早期检测脓毒症病原体的临床应用进展.

Sepsis patients have low survival rates, high mortality rates, and poor prognosis, making early identification of pathogens particularly crucial. Metagenomic next-generation sequencing (mNGS) enables unbiased detection of all microorganisms in clinical samples, providing greater sensitivity, accuracy, and efficiency in early detection of sepsis pathogenic microorganism compared to traditional culture techniques. With the continuous development of next-generation sequencing technology, the clinical application value of mNGS in sepsis diagnosis will further improve. This article reviews the advantages, clinical applications, progress, challenges, and prospects of mNGS in the early diagnosis of sepsis. [ABSTRACT FROM AUTHOR]