Histological sampling protocols for transurethral resection of prostate specimens need reappraisal.

The article discusses the need to reassess the histological sampling protocols for transurethral resection of prostate (TURP) specimens. Currently, these specimens are sampled extensively, even when there is no clinical or macroscopic evidence of malignancy. The authors argue that this practice is costly and time-consuming, and they call for a more pragmatic and cost-effective approach to sampling. They suggest that sampling protocols should focus on detecting clinically significant cancer rather than incidental cancer. The authors recommend a joint initiative by the Genitourinary Pathology Society (GUPS) and the International Society of Urological Pathology (ISUP) to review and recommend changes to current practice. [Extracted from the article]