Back to Search Start Over

Cluster Analysis Identifies Patients With Severe Eosinophilic Asthma Who Achieve Super‐Response and Remission With Mepolizumab.

Authors :
Di Bona, Danilo
Bilancia, Massimo
Crimi, Claudia
Daddato, Michelina
Benfante, Alida
Caiaffa, Maria Filomena
Calabrese, Cecilia
Campisi, Raffaele
Nolasco, Santi
Carpagnano, Giovanna Elisiana
D'Amato, Maria
Pelaia, Corrado
Pelaia, Girolamo
Maglio, Angelantonio
Scichilone, Nicola
Scioscia, Giulia
Spadaro, Giuseppe
Triggiani, Massimo
Carrieri, Isabella
Valenti, Giuseppe
Source :
Clinical & Experimental Allergy. Oct2024, p1. 3p. 2 Illustrations.
Publication Year :
2024

Abstract

This article discusses a study that examined the effectiveness of the drug mepolizumab in treating severe eosinophilic asthma (SEA). The study used cluster analysis to identify two subgroups of patients with SEA, with Cluster 2 (C2) showing higher rates of response to the medication compared to Cluster 1 (C1). The study also found that family history of asthma was a predictor of treatment response. The research suggests that personalized treatment strategies based on subgroup identification could be beneficial for patients with SEA. Further validation studies are needed to confirm these findings. [Extracted from the article]

Details

Language :
English
ISSN :
09547894
Database :
Academic Search Index
Journal :
Clinical & Experimental Allergy
Publication Type :
Academic Journal
Accession number :
180186453
Full Text :
https://doi.org/10.1111/cea.14584