Discovery of New Compound Comazaphilone I from Mycolicibacterium aurum.

A new compound, comazaphilone I (1), was isolated from Mycolicibacterium aurum WYQ isolated from marine sediment samples collected in the East China Sea. Its structure was elucidated based on spectroscopic data, comparison with literature data, and ECD calculation. The newly discovered compound, while bearing a similar planar structure to the known compound comazaphilone A, features a distinct 6S7S configuration. However, no bioactivities were screened from the bioassay experiments. [ABSTRACT FROM AUTHOR]