A Simple Method for the Synthesis of Pyrazolo[1,2-c]benzo-1,3,4-thiadiazepine Derivatives Based on Formaldehyde, Acrolein, and 2-Mercaptobenzoic Acid Hydrazide.

The two-step method for the synthesis of previously unknown 1-hydroxy-2,3-dihydropyrazolo[1,2-c]-benzo-1,3,4-thiadiazepin-11(5H)-one has been developed based on 2-mercaptobenzoic acid hydrazide and commercially available formaldehyde and acrolein. The synthesized compound, which has a targeted antitumor effect, is a promising bioactive co-ligand for obtaining gold glyco-nanoparticles for biomedical purposes. [ABSTRACT FROM AUTHOR]