基于影像组学预测大脑年龄与缺血性 卒中的研究进展.

As an individualized brain health imaging phenotype, brain age is a new neuroimaging biomarker to assess the degree of brain aging. The discrepancy between an individual’s brain age and chronological age, known as the predicted age difference, reflects the trajectory and rate of brain aging. Previous studies have found that a greater predicted age difference in patients with ischemic stroke was associated with poor prognosis. Furthermore, ischemic brain injury may accelerate the brain aging process in stroke patients, suggesting the potential for a vicious cycle between brain aging and ischemic stroke. This article reviewed the progress in research on brain age prediction methodologies, factors influencing the rate of brain aging, the relationship between brain age and ischemic stroke, and the integration of multi-omics data analysis, providing a fresh perspective for biogerontological research related with stroke [ABSTRACT FROM AUTHOR]