国外转基因作物上草铵膦登记残留风险评估进展.

This paper highlights the progress made by the Joint FAO/WHO Meeting on Pesticide Residues (JMPR), the European Union European Food Safety Authority (EFSA), the U.S. Environmental Protection Agency (EPA), and the Japanese Pharmaceutical Affairs and Food Sanitation Council (PAFSC) on the residues risk assessment of glufosinate-ammonium registration on transgenic crops, focusing on the metabolism of glufosinate-ammonium in transgenic crops, the animal metabolism, the methods of residue analysis, storage stability, supervised residue trials, toxicological evaluation, residue definitions, and maximum residue limit (MRL) setting were summarized and analyzed. Compared with non-genetically modified crops, new metabolic pathways have emerged after the use of glufosinate-ammonium in transgenic crops. The metabolite N-acetyl-glufosinate (NAG) is the main residue of glufosinate-ammonium in transgenic crops, and thus relevant countries and organizations have included it in the residue definition of glufosinate-ammonium. The higher residue levels of glufosinate-ammonium in transgenic crops than in non-genetically modified crops are mainly related to the technical characteristics of glufosinate-ammonium use on transgenic crops and the emergence of new metabolites. Currently, no distinction is made between non-genetically modified crops and transgenic crops on MRLs for glufosinate-ammonium. The authors believe that when carrying out risk assessment of pesticide residues in transgenic crops, corresponding metabolism tests should be carried out first, and residue data should be reasonably selected based on the principle of risk. maximization to formulate uniform MRLs. This paper can provide a reference for improving the technical level of pesticide residue risk assessment and developing MRL standards for pesticide application on transgenic crops in China. [ABSTRACT FROM AUTHOR]