Comparison of nail changes in chronic kidney disease under haemodialysis with patients on oral maintenance therapy.

Objective To compare the frequency of nail changes in Chronic Kidney Disease patients undergoing haemodialysis with patients on maintenance therapy. Methods This analytical cross-sectional study was carried out at Dermatology and Nephrology Department, Sahiwal Teaching Hospitals, Sahiwal, after approval from Institutional Ethical Review Committee. A total of 158 patients with chronic kidney disease of either sex and age were divided into two groups: Group A (patients under regular haemodialysis) Group B (patients on oral therapy). Patient's demographic, clinical and laboratory data were recorded in predesigned proforma. Data were analyzed by using SPSS version 28. Results Out of total 158 patients, male female ratio was 1.1:1 and majority of patients (63.3%) were above age of 40 years. Most commonly reported nail changes in both groups were absence of lunula (65%, 57%), longitudinal ridging (54%, 58%) and onycholysis (45%, 35%) but variations were observed in their frequencies. There was no statistically significant difference in nail changes of both groups. Conclusion Patients with CKD undergoing HD therapy have slight higher frequency of nail changes compared to patients on maintenance therapy. Further studies with large sample size may elaborate Results. [ABSTRACT FROM AUTHOR]