Multiple drugs: Lack of efficacy: 2 case reports.

The article from Reactions Weekly discusses two case reports of elderly patients with chronic lymphocytic leukaemia (CLL) who exhibited lack of efficacy during treatment with various drugs. In the first case, a woman with CLL did not respond to daratumumab and eventually died due to disease progression. In the second case, a patient with CLL and breast cancer experienced worsening clinical condition despite treatment with multiple drugs, leading to death from disease progression. [Extracted from the article]