上海市35~75岁社区居民心血管病危险因素聚集与静息心率升高的关联性研究

Objective To explore the association between the accumulation of cardiovascular risk factors and the elevated resting heart rate in community residents aged 35-75 years in Shanghai [WTHZ]Methods [WTBZ]Participates were obtained from the China PEACE Million Persons Projects. 8 districts in Shanghai were selected from 2017 to 2019, and the screening was carried out between adults aged 35 to 75 years in communities. Questionnaires, physical examinations and laboratory tests were conducted. The Kruskal-Wallis test and Cochran-Mantel-Haenszel test were used to compare groups by using R 4.2.2 software. Multivariate logistic regression was performed to explore the correlation between the number of common risk factors for cardiovascular diseases, the combination of different risk factors and elevated resting heart rate. [WTHZ]Results [WTBZ]Among 87934 participants, the mean age was 59.1±9.7 years. Compared with the group with no risk factors, the OR(95%CI) for elevated resting heart rate for the groups with 1, 2, 3 and ≥4 risk factor were 1.42（1.36-1.47）、1.70（1.53-1.77）、1.94（1.84-2.05）and 2.17（1.99-2.36）, respectively. The risk of elevated RHR was the most strongly influenced by the cardiovascular risk factor clustering number in the female group aged 35 to 44 with ≥4 risk factors, and the OR(95%CI) was 3.77 (2.10-4.27). In the combination of risk factors, more metabolic risk factors were associated with a higher risk of elevated resting heart rate. [WTHZ]Conclusion [WTBZ]Resting heart rate may serve as a simple and practical indicator of the cumulative effect of multiple cardiovascular risk factors, which can help early identification of individuals at high cardiovascular risk in relatively healthy people, so as to enable early intervention. [ABSTRACT FROM AUTHOR]