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Diverse wild-derived inbred strains provide a new community resource.

Authors :
Nachman, Michael W.
Dumont, Beth L.
Source :
Mammalian Genome. Dec2024, Vol. 35 Issue 4, p551-555. 5p.
Publication Year :
2024

Abstract

The article discusses the development and release of 11 new wild-derived inbred mouse strains known as the "Nachman panel," which offer a unique genetic and phenotypic diversity platform for biological research. These strains were developed from wild-caught mice from different geographic regions in North and South America, providing a wide range of genetic and phenotypic variation. The Nachman strains have been extensively characterized genetically and phenotypically, offering a rich resource for biological discovery and disease modeling. Despite some limitations, such as smaller litter sizes and wild behavior, these strains present promising prospects for future research in basic, biomedical, and preclinical investigations. [Extracted from the article]

Details

Language :
English
ISSN :
09388990
Volume :
35
Issue :
4
Database :
Academic Search Index
Journal :
Mammalian Genome
Publication Type :
Academic Journal
Accession number :
180587132
Full Text :
https://doi.org/10.1007/s00335-024-10061-4