Structural Elucidation and Complete NMR Spectral Assignments of Monascus Monacolin Analogs.

ABSTRACT One new monacolin analog, monacolin V (<bold>1</bold>), together with two new monacolin‐like natural products, 6‐hydroxyl monacolin P (<bold>2</bold>) and 3‐keto monacolin S (<bold>3</bold>), were isolated from the ethyl acetate portion of red yeast rice ethanol extract. Their structures were identified by HRESIMS and NMR experiments, and the complete assignments of 1H and 13C NMR data for three compounds were obtained by the aid of HSQC, HMBC, 1H‐1H COSY, and NOESY data. This is the first time that the NMR data of compounds <bold>2</bold> and <bold>3</bold> have been fully assigned. [ABSTRACT FROM AUTHOR]