PP 1/331 (1) Principles of efficacy extrapolations for major uses.

The document titled "PP 1/331 (1) Principles of efficacy extrapolations for major uses" outlines the principles to be followed when considering effectiveness and crop safety extrapolations of plant protection products applied for major uses. The aim is to reduce the need for trial data on individual major crop and major pest situations while maintaining appropriate data sets. The document provides guidance for regulatory authorities and applicants in the context of product registration and does not cover plant growth regulators or extrapolations of identical uses between different formulations of the same product. It also discusses specific effectiveness extrapolations for fungicides, insecticides or acaricides, and herbicides, with decision-making schemes provided in the appendix. [Extracted from the article]