Back to Search
Start Over
A New Amide from the Fermentation of Fusarium sp. SFS-G3 and Cytotoxic Activities.
- Source :
-
Chemistry of Natural Compounds . Nov2024, Vol. 60 Issue 6, p1080-1083. 4p. - Publication Year :
- 2024
-
Abstract
- N-(5-((3E,5E)-10-Acetoxy-5,7,9,11-tetramethyltrideca-3,5-dien-1-yl)-2-oxotetrahydrofuran-3-yl)acetamide (1), a new amide compound, and five known ones (2–6) were isolated from the EtOH extract of the solid culture of Fusarium sp. Their structures were determined by means of extensive 1D and 2D NMR techniques, as well as comparison with literature values. Additionally, compounds 1–6 were tested for their cytotoxic activities. The results showed that compounds 2, 3, 6 exhibited cytotoxic activities against five human cancer cell lines with IC50 values ranging from 2.088 to 26.40 μM. [ABSTRACT FROM AUTHOR]
- Subjects :
- *CELL lines
*CANCER cells
*FUSARIUM
*FERMENTATION
*ACETAMIDE
*LITERATURE
Subjects
Details
- Language :
- English
- ISSN :
- 00093130
- Volume :
- 60
- Issue :
- 6
- Database :
- Academic Search Index
- Journal :
- Chemistry of Natural Compounds
- Publication Type :
- Academic Journal
- Accession number :
- 180934783
- Full Text :
- https://doi.org/10.1007/s10600-024-04524-y