Impact of environmental factors on the severity of rosacea: Multicentre Observational study.

Background: Rosacea is a chronic inflammatory skin condition that can be exacerbated by various environmental factors. This study aimed to investigate the impact of UV radiation, temperature, humidity, and air pollution on rosacea severity and quality of life over a one-year period. Methods: A prospective observational study was conducted with 100 adult rosacea patients. Rosacea severity (assessed using the National Rosacea Society Expert Committee grading system) and quality of life (assessed using the Dermatology Life Quality Index) were evaluated at baseline and every three months for one year. Participants kept daily diaries of their exposure to environmental factors. Results: Significant associations were found between environmental factors and rosacea severity. UV radiation (coefficient 0.18, 95% CI 0.10-0.26, p<0.001), temperature (coefficient 0.14, 95% CI 0.08-0.20, p<0.001), humidity (coefficient 0.09, 95% CI 0.03-0.15, p=0.004), and air pollution (coefficient 0.12, 95% CI 0.06-0.18, p<0.001) were all significantly associated with increased rosacea severity. Rosacea severity scores decreased significantly from baseline to each follow-up visit (p<0.001), and quality of life scores improved significantly (p<0.001). Subgroup analyses revealed consistent findings across age groups, genders, and rosacea subtypes. Conclusion: Exposure to UV radiation, high temperatures, humidity, and air pollution were significantly associated with increased rosacea severity and reduced quality of life. These findings emphasize the importance of environmental factor management in the treatment and prevention of rosacea flare-ups. [ABSTRACT FROM AUTHOR]