Back to Search
Start Over
Antigen-specific CD4+ regulatory T cells in cancer: implications for immunotherapy
- Source :
-
Microbes & Infection . Jun2005, Vol. 7 Issue 7/8, p1056-1062. 7p. - Publication Year :
- 2005
-
Abstract
- Abstract: Regulatory T cells play essential roles in inducing self-tolerance by suppressing immune responses against self such as autoantigens or non-self-antigens such as tumor and pathogenic antigens. Despite the importance of CD4+ regulatory T cells in many immune-related diseases, their antigen specificity and suppressive mechanisms remain elusive. This review discusses the natural ligands and their potential roles of tumor-specific CD4+ regulatory T cells in cancer therapy. [Copyright &y& Elsevier]
- Subjects :
- *LYMPHOCYTES
*T cells
*PREVENTIVE medicine
*IMMUNOGLOBULINS
Subjects
Details
- Language :
- English
- ISSN :
- 12864579
- Volume :
- 7
- Issue :
- 7/8
- Database :
- Academic Search Index
- Journal :
- Microbes & Infection
- Publication Type :
- Academic Journal
- Accession number :
- 18153168
- Full Text :
- https://doi.org/10.1016/j.micinf.2005.03.028