Photodynamic Therapy in Cancer: Principles, State of the Art, and Future Directions.

The document "Photodynamic Therapy in Cancer: Principles, State of the Art, and Future Directions" published in the journal Pharmaceutics discusses the use of photodynamic therapy (PDT) as a potent strategy for treating various types of cancer. PDT involves photoactive dyes that, when exposed to light, trigger the production of cytotoxic molecules in tumor tissue. Advances in light delivery systems have expanded the applicability of PDT to treat large solid tumors and tumors deep within organs. The document highlights the development of new photoactive molecules, the importance of inducing immunogenic cell death, and the potential of combining PDT with other cancer treatment modalities to enhance efficacy. [Extracted from the article]