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Avatrombopag in adults with immune thrombocytopenia: A multicentre real‐life observational study in Madrid, Spain (AVAMAD study)

Authors :
Pascual‐Izquierdo, Cristina
Llacer‐Ferrandis, Mª. Jose
de‐la‐Iglesia, Almudena
Monsalvo‐Saornil, Silvia
Menor‐Gómez, María
Gil‐Fernández, Juan Jose
Chica‐Gullon, Esther
Álvarez‐Román, María Teresa
Perez‐Segura, Gloria
Zafra, Denis
Ortuzar‐Pasalodos, Ariana
González‐Gascón‐y‐Marín, Isabel Teresa
Moreno, Gemma
Arquero‐Portero, Teresa
Moreno‐Carbonell, Marta
Revilla, Nuria
Source :
British Journal of Haematology. Jan2025, p1. 5p. 1 Illustration.
Publication Year :
2025

Abstract

Summary Immune thrombocytopenia (ITP) is a rare acquired disorder where thrombopoietin‐receptor agonists have become mainstays of ITP treatment. With the recent approval of avatrombopag (AVA), real‐world studies are essential to evaluate its efficacy and safety. Our study of 66 adult ITP patients treated with AVA showed a high response rate. After starting AVA, 74.2% did not require rescue medications, with minimal adverse effects. Additionally, 56.0% of patients reduced other ITP medications, and all patients aged ≥65 years responded to AVA. Results should be confirmed in larger studies, but AVA appears to be an effective and safe treatment for ITP patients. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
00071048
Database :
Academic Search Index
Journal :
British Journal of Haematology
Publication Type :
Academic Journal
Accession number :
182045681
Full Text :
https://doi.org/10.1111/bjh.19975