The revival of cyclodextrins as active pharmaceutical ingredients.

The article discusses the revival of cyclodextrins as active pharmaceutical ingredients, highlighting their unique molecular structure and biocompatible properties. Cyclodextrins have been traditionally used as excipients in pharmaceutical formulations but are now being explored as active ingredients in treating various diseases such as COVID-19, neuromuscular blockade, Stargardt, hemophilia, atherosclerosis, Alzheimer's, Parkinson's, diabetic kidney disease, dry eye disease, focal segmental glomerulosclerosis, Alport syndrome, and Niemann–Pick C. The potential of cyclodextrins as artificial receptors or cholesterol modulators is also explored, showing promise in scavenging toxic compounds and modulating cholesterol levels in the body. The article emphasizes the need for further research to standardize the synthesis process of cyclodextrin derivatives and understand their long-term effects. [Extracted from the article]