Back to Search
Start Over
Thermodynamics of non-stoichiometric pharmaceutical hydrates
- Source :
-
International Journal of Pharmaceutics . Oct2005, Vol. 303 Issue 1/2, p37-53. 17p. - Publication Year :
- 2005
-
Abstract
- Abstract: Different physical and mathematical models of non-stoichiometric hydrates derived form previous work in inorganic hydrates are reviewed. A theoretical link between the order of water molecules in the hydrate and the shape of the isotherm is outlined. The comparison of the models with sorption isotherms and structural data of well-known cases from the literature and one in-house case shows that the model can fit many experimental situations and is in good agreement with qualitative assessments of the order in the hydrates. [Copyright &y& Elsevier]
- Subjects :
- *HYDRATES
*DRUGS
*ABSORPTION
*ATMOSPHERIC temperature
Subjects
Details
- Language :
- English
- ISSN :
- 03785173
- Volume :
- 303
- Issue :
- 1/2
- Database :
- Academic Search Index
- Journal :
- International Journal of Pharmaceutics
- Publication Type :
- Academic Journal
- Accession number :
- 18343140
- Full Text :
- https://doi.org/10.1016/j.ijpharm.2005.07.007