Chronic myeloid leukemia CD34+ cells have elevated levels of phosphatidylinositol 3,4,5 trisphosphate (PtdIns(3,4,5)P3) and lack a PtdIns(3,4,5)P3 response to cytokines and chemotactic factors; effects reversed by imatinib.

Authors :: Hamzah, H. G.
Pierce, A.
Stewart, W. A.
Downes, C. Peter
Gray, A.
Irvine, A.
Spooncer, E.
Whetton, A. D.
Source :: Leukemia (08876924). Oct2005, Vol. 19 Issue 10, p1851-1853. 3p. 3 Graphs.
Publication Year :: 2005
Abstract: Presents a letter to the editor in response to the article "Chronic Myeloid Leukemia CD34+ Cells Have Elevated Levels of Phosphatidylinositol 3,4,5 Trisphosphate (PtdIns(3,4,5)P3) and Lack a PtdIns(3,4,5)P3 Response to Cytokines and Chemotactic Factors; Effects Reversed by Imatinib," previously published in the journal "Leukemia."

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