Desalting of Proteins Using MassPREP On-line Desalting Cartridges Prior to Mass Spectrometry.

Describes the use of the liquid chromatography-mass spectrometry as a tool for the characterization of proteins. Efficacy of the separation technique as an approach for the desalting of proteins; Importance of the separation of proteins from non-volatile salts as a step prior to introduction into the mass spectrometer; Determination of loading capacity of monoclonal immunoglobulin G.